BP103T. PHARMACEUTICS-I (Theory)

Unit-I (10 Hours)

Historical Background and Development of Pharmacy

• History of Pharmacy in India: Education, Industry, and Organization.
• Pharmacy as a Career.
• Pharmacopoeias: Introduction to IP, BP, USP, and Extra Pharmacopoeia.

Dosage Forms

• Introduction, Classification, and Definitions of Dosage Forms.

Prescription

• Definition, Parts of Prescription, Handling of Prescription, and Errors in Prescription.

Posology

• Definition and Factors Affecting Posology.
• Pediatric Dose Calculations: Based on Age, Body Weight, and Body Surface Area.

Unit-II (10 Hours)

Pharmaceutical Calculations

• Weights and Measures: Imperial & Metric System.
• Calculations: Percentage Solutions, Allegation, Proof Spirit, and Isotonic Solutions (based on freezing point and molecular weight).

Powders

• Definition, Classification, Advantages, and Disadvantages.
• Types: Simple & Compound Powders, Dusting Powders, Effervescent, Efflorescent, Hygroscopic Powders, and Eutectic Mixtures.
• Geometric Dilutions.

Liquid Dosage Forms

• Advantages and Disadvantages.
• Excipients Used in Formulations.
• Solubility Enhancement Techniques.

Unit-III (10 Hours)

Monophasic Liquids

• Definitions and Preparations of:
  • Gargles
  • Mouthwashes
  • Throat Paints
  • Eardrops
  • Nasal Drops
  • Enemas
  • Syrups
  • Elixirs
  • Liniments
  • Lotions

Biphasic Liquids

• Suspensions:
  • Definition, Advantages, and Disadvantages.
  • Classification and Preparation of Suspensions.
  • Flocculated vs. Deflocculated Suspensions.
  • Stability Problems and Methods to Overcome Them.
• Emulsions:
  • Definition and Classification.
  • Emulsifying Agents and Tests for Identification.
  • Methods of Preparation, Stability Problems, and Solutions.

Unit-IV (08 Hours)

Suppositories

• Definition, Types, Advantages, and Disadvantages.
• Types of Bases and Methods of Preparation.
• Displacement Value and Its Calculations.
• Evaluation of Suppositories.

Pharmaceutical Incompatibilities

• Definition and Classification.
• Types: Physical, Chemical, and Therapeutic Incompatibilities with Examples.

Unit-V (07 Hours)

Semisolid Dosage Forms

• Definitions and Classification.
• Mechanisms and Factors Influencing Dermal Penetration of Drugs.
• Preparation of:
  • Ointments
  • Pastes
  • Creams
  • Gels
• Excipients Used in Semi-Solid Dosage Forms.
• Evaluation of Semi-Solid Dosage Forms.