Unit-I (06 Hours)
Partial fraction:
- Introduction, Polynomial, Rational fractions, Proper and Improper fractions, Partial fraction, Resolving into Partial fraction, Application of Partial Fraction in Chemical Kinetics and Pharmacokinetics.
Logarithms:
- Introduction, Definition, Theorems/Properties of logarithms, Common logarithms, Characteristic and Mantissa, worked examples, application of logarithm to solve pharmaceutical problems.
Function:
- Real Valued function, Classification of real valued functions.
Limits and continuity:
- Introduction, Limit of a function, Definition of limit of a function (∈ – δ definition),
Unit-II (06 Hours)
Matrices and Determinant:
- Introduction to matrices, Types of matrices, Operation on matrices, Transpose of a matrix, Matrix Multiplication, Determinants, Properties of determinants, Product of determinants, Minors and co-Factors, Adjoint or adjugate of a square matrix, Singular and non-singular matrices, Inverse of a matrix.
- Solution of system of linear equations using matrix method, Cramer’s rule.
- Characteristic equation and roots of a square matrix, Cayley-Hamilton theorem.
- Application of Matrices in solving Pharmacokinetic equations.
Unit-III (06 Hours)
Calculus Differentiation:
- Introductions, Derivative of a function, Derivative of a constant, Derivative of a product of a constant and a function, Derivative of the sum or difference of two functions.
- Derivative of the product of two functions (product formula), Derivative of the quotient of two functions (Quotient formula) – Without Proof.
- Derivative of w.r.t , where is any rational number.
- Derivative of , Derivative of , Derivative of .
- Derivative of trigonometric functions from first principles (without Proof).
- Successive Differentiation, Conditions for a function to be a maximum or a minimum at a point.
- Applications.
Unit-IV (06 Hours)
Analytical Geometry:
- Introduction: Signs of the Coordinates, Distance formula.
- Straight Line: Slope or gradient of a straight line, Conditions for parallelism and perpendicularity of two lines, Slope of a line joining two points, Slope – intercept form of a straight line.
Integration:
- Introduction, Definition, Standard formulae, Rules of integration.
- Method of substitution, Method of Partial fractions, Integration by parts, definite integrals, applications.
Unit-V (06 Hours)
Differential Equations:
- Some basic definitions, Order and degree, Equations in separable form, Homogeneous equations, Linear Differential equations, Exact equations.
- Applications in solving Pharmacokinetic equations.
Laplace Transform:
- Introduction, Definition, Properties of Laplace transform.
- Laplace Transforms of elementary functions, Inverse Laplace transforms, Laplace transform of derivatives.
- Applications to solve Linear differential equations.
- Applications in solving chemical kinetics and Pharmacokinetics equations.

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