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Unit-I: General Pharmacology
- Introduction to pharmacology: Definition, historical landmarks, and scope of pharmacology.
- Nature and sources of drugs, essential drug concepts, and routes of drug administration.
- Concepts of agonists, antagonists (competitive and non-competitive), spare receptors.
- Concepts of drug addiction, tolerance, dependence, tachyphylaxis, idiosyncrasy, and allergy.
- Pharmacokinetics: Membrane transport, absorption, distribution, metabolism, and excretion of drugs.
- Enzyme induction, enzyme inhibition, and kinetics of elimination.
Unit-II: General Pharmacology
- Pharmacodynamics: Principles and mechanisms of drug action.
- Receptor theories and classification, regulation of receptors, drug-receptor interactions.
- Signal transduction mechanisms: G-protein–coupled receptors, ion channel receptors, transmembrane enzyme-linked receptors, and JAK-STAT binding receptors.
- Dose-response relationship and therapeutic index.
- Combined effects of drugs and factors modifying drug action.
- Adverse drug reactions and drug interactions (pharmacokinetic and pharmacodynamic).
- Drug discovery and clinical evaluation of new drugs: Phases of clinical trials and pharmacovigilance.
Unit-III: Pharmacology of Drugs Acting on Peripheral Nervous System
- Organization and function of the autonomic nervous system (ANS).
- Neurohumoral transmission, co-transmission, and classification of neurotransmitters.
- Drugs affecting the ANS: Parasympathomimetic, parasympatholytic, sympathomimetic, and sympatholytic agents.
- Neuromuscular blocking agents and skeletal muscle relaxants (peripheral).
- Local anesthetic agents.
- Drugs used in myasthenia gravis and glaucoma.
Unit-IV: Pharmacology of Drugs Acting on Central Nervous System
- Neurohumoral transmission in the CNS and the role of neurotransmitters like GABA, Glutamate, Glycine, serotonin, and dopamine.
- General anesthetics and pre-anesthetics.
- Sedatives, hypnotics, and centrally acting muscle relaxants.
- Anti-epileptic drugs.
- Alcohols and disulfiram.
Unit-V: Pharmacology of Drugs Acting on Central Nervous System
- Psychopharmacological agents: Antipsychotics, antidepressants, anti-anxiety agents, antimanic drugs, and hallucinogens.
- Drugs used in Parkinson’s disease and Alzheimer’s disease.
- CNS stimulants and nootropics.
- Opioid analgesics and antagonists.
- Drug addiction, drug abuse, tolerance, and dependence.
I have 4 years of experience in blogging and I am also a pharmacist.
