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Unit-I: Pharmacology of Drugs Acting on the Cardiovascular System
- Introduction to hemodynamic and electrophysiology of the heart.
- Drugs used in congestive heart failure.
- Anti-hypertensive drugs.
- Anti-anginal drugs.
- Anti-arrhythmic drugs.
- Anti-hyperlipidemic drugs.
Unit-II: Drugs Used in Shock and Coagulation Disorders
- Drugs used in the therapy of shock.
- Hematinics, coagulants, and anticoagulants.
- Fibrinolytics and anti-platelet drugs.
- Plasma volume expanders.
Unit-III: Autacoids and Related Drugs
- Introduction to autacoids and their classification.
- Histamine, 5-HT, and their antagonists.
- Prostaglandins, Thromboxanes, and Leukotrienes.
- Angiotensin, Bradykinin, and Substance P.
- Non-steroidal anti-inflammatory agents.
- Anti-gout and anti-rheumatic drugs.
Unit-IV: Pharmacology of Drugs Acting on the Endocrine System
- Basic concepts in endocrine pharmacology.
- Anterior Pituitary hormones – analogs and their inhibitors.
- Thyroid hormones – analogs and their inhibitors.
- Hormones regulating plasma calcium levels – Parathormone, Calcitonin, and Vitamin D.
- Insulin, Oral Hypoglycemic agents, and glucagon.
- ACTH and corticosteroids.
Unit-V: Drugs Acting on the Endocrine System and Bioassay
- Androgens and Anabolic steroids.
- Estrogens, progesterone, and oral contraceptives.
- Drugs acting on the uterus.
- Bioassay:
- Principles and applications.
- Types of bioassay.
- Bioassay of insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine, and 5-HT.
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