BP704T. NOVEL DRUG DELIVERY SYSTEM (NDDS) (Theory)

Unit-I

Introduction to NDDS:

• Definition, need, and advantages of novel drug delivery systems.
• Classification of NDDS.
• Factors influencing the design of drug delivery systems.

Controlled Drug Delivery Systems:

• Principles, types, and advantages.
• Polymers in controlled drug delivery systems.

Unit-II

Targeted Drug Delivery Systems:

• Concept and importance.
• Types of targeting: Passive and active targeting.
• Applications in cancer therapy and infectious diseases.

Transdermal Drug Delivery Systems (TDDS):

• Components and formulation.
• Mechanism of drug permeation.
• Evaluation of TDDS.

Unit-III

Mucosal Drug Delivery Systems:

• Buccal, nasal, and ocular drug delivery systems.
• Formulation considerations and evaluation.

Gastro-retentive Drug Delivery Systems:

• Mechanisms for gastric retention.
• Formulation approaches: Floating, mucoadhesive, and swelling systems.

Unit-IV

Particulate Drug Delivery Systems:

• Microspheres, nanoparticles, and liposomes.
• Preparation methods and pharmaceutical applications.
• Evaluation of particulate systems.

Pulmonary Drug Delivery Systems:

• Formulation and evaluation of inhalation products.
• Applications in respiratory diseases.

Unit-V

Recent Advances in NDDS:

• Smart drug delivery systems.
• Stimuli-responsive drug delivery systems.
• Nanotechnology in drug delivery.
• Regulatory aspects of NDDS development.